Magnesium boosts the memory restorative effect of environmental enrichment in Alzheimer's disease mice.

Ying HuangXian HuangLing ZhangFang HanKe-Liang PangXue LiJian-Ying Shen

Published in: CNS neuroscience & therapeutics (2017)

Environmental enrichment and MgT may synergistically improve recognition and spatial memory by reducing synaptic loss and restoring the NMDAR signaling pathway in AD mice, which suggests that combination of EE and MgT may be a novel therapeutic strategy for AD.

Keyphrases

signaling pathway
high fat diet induced
working memory
pi k akt
life cycle
oxidative stress
risk assessment
insulin resistance
metabolic syndrome
type diabetes
adipose tissue
induced apoptosis