Assessment of runs of homozygosity islands and estimates of genomic inbreeding in Gyr (Bos indicus) dairy cattle.

Elisa PeripolliNedenia Bonvino StafuzzaDanísio Prado MunariAndré Luís Ferreira LimaRenato IrgangMarco Antonio MachadoJoão Cláudio do Carmo PanettoRicardo Vieira VenturaFernando BaldiMarcos Vinícius Gualberto Barbosa da Silva

Published in: BMC genomics (2018)

Genes inside ROH islands suggest a strong selection for dairy traits and enrichment for Gyr cattle environmental adaptation. Furthermore, low FPED-FROH correlations for small segments indicate that FPED estimates are not the most suitable method to capture ancient inbreeding. The existence of a moderate correlation between larger ROH indicates that FROH can be used as an alternative to inbreeding estimates in the absence of pedigree records.

Keyphrases

genome wide
high intensity
gene expression
dna methylation
risk assessment