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Vitamin D3 supplementation and treatment outcomes in patients with depression (D3-vit-dep).

Jens Peter HansenManan PareekAllan HvolbyAnne SchmedesTomas ToftErik DahlConnie Thurøe Nielsen
Published in: BMC research notes (2019)
At baseline, 23 patients had a normal 25(OH)D level, 22 had insufficiency (< 25 nmol/L), and 17 had deficiency (25-50 nmol/L). No significant reduction in depression was seen after vitamin D supplementation compared to placebo at Hamilton (18.4-18.0; p = 0.73 at 12 weeks). Vitamin D supplementation did not provide a reduction in symptom score among patients with depression. Trial registration The trial was registered in the National Board of Health (EudraCT: 2011-002585-20) and in ClinicalTrials.Gov (NCT01390662).
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