Changes in alanine aminotransferase levels after switching from tenofovir disoproxil fumarate (TDF) to tenofovir alafenamide (TAF) in HIV-positive people without viral hepatitis in the Swiss HIV Cohort Study.
Helen KovariB SurialP E TarrM CavassiniA CalmyP SchmidE BernasconiA RauchG WandelerB Ledergerbernull nullPublished in: HIV medicine (2021)
Replacing TDF with TAF in HIV-monoinfected people led to a significant decrease in ALT values. Findings were not significantly affected by known risk factors for hepatotoxicity.