Blood flow response to orthostatic challenge identifies signatures of the failure of static cerebral autoregulation in patients with cerebrovascular disease.

Clara Gregori-PlaRickson C MesquitaChristopher G FavillaDavid R BuschIgor BlancoPeyman ZirakLisa Kobayashi FriskStella AvtziFederica MarucciaGiacomo GiacaloneGianluca CottaPol Camps-RenomMichael T MullenJoan Martí-FàbregasLuís Prats-SánchezAlejandro Martínez-DomeñoScott E KasnerJoel H GreenbergChao ZhouBrian L EdlowMary E PuttJohn A DetreArjun G YodhTurgut DurduranRaquel Delgado-Mederos

Published in: BMC neurology (2021)

The observed associations between ipsilateral CBF and MAP suggest that short HOB position changes may elicit deficits in cerebral autoregulation in cerebrovascular disorders. Additional research is required to further characterize this phenomenon.

Keyphrases

blood flow
cerebral blood flow
subarachnoid hemorrhage
genome wide
traumatic brain injury
cerebral ischemia
brain injury
dna methylation
gene expression