The KRAS G12D mutation increases the risk of unresectable recurrence of resectable colorectal liver-only metastasis.
Kai ChenYukiyasu OkamuraKeiichi HatakeyamaAkio ShiomiHiroyasu KagawaHitoshi HinoShoichi ManabeYusuke YamaokaTeiichi SugiuraTakashi SuginoAkifumi NotsuTakeshi NagashimaKeiichi OhshimaKenichi UrakamiYasuto AkiyamaKen YamaguchiPublished in: Surgery today (2024)
This is the first study to show that specific KRAS and RYR2 mutations were associated with the URFS.