Initial experience of preoperative short-course radiotherapy followed by oxaliplatin-based consolidation chemotherapy for locally advanced rectal cancer.

Seung Ho SongJun Seok ParkMin Kyu KangGyu-Seog ChoiSoo Yeun ParkHye Jin KimJong Gwang KimByung Woog KangJin Ho BaekDong Won BaekJae-Chul KimShin-Hyung ParkSeung Hyun ChoAn Na Seo

Published in: International journal of colorectal disease (2021)

Preoperative SCRT followed by oxaliplatin-based consolidation chemotherapy showed acceptable toxicity and feasibility in patients with LARC. Prospective randomized trials are warranted to verify the efficacy and safety of this treatment strategy compared with conventional long-course concurrent chemoradiotherapy.

Keyphrases

locally advanced
rectal cancer
squamous cell carcinoma
radiation therapy
patients undergoing
oxidative stress
early stage
radiation induced