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Platelet storage pool disorder in pregnancy: Utilising thromboelastography to guide a risk-based delivery plan.

Timothy Arthur Chandos SnowRezan A Abdul-KadirKeith GomezAdrian England
Published in: Obstetric medicine (2021)
We present a case of a 33-year-old woman in her third pregnancy diagnosed with platelet storage pool disorder who had previously suffered two postpartum major obstetric haemorrhages. Platelet storage pool disorder is a rare bleeding disorder where the platelet count is normal but platelet function is impaired due to deficiency of dense granules. A peripartum plan devised by an extensive multi-disciplinary team using principles for managing other bleeding and platelet function disorders helped minimise her risk of major haemorrhage. We also describe how point-of-care thromboelastography can help guide management and enable an individualised risk-benefit discussion with the woman about her anaesthetic choices.
Keyphrases
  • atrial fibrillation
  • preterm birth
  • pregnant women
  • palliative care
  • pregnancy outcomes
  • replacement therapy