Title: insoluble proteins catch heterologous soluble proteins into inclusion bodies by intermolecular interaction of aggregating peptides.
Jose Vicente CarrataláAndrés CisnerosElijah HellmanAntonio VillaverdeNeus Ferrer-MirallesPublished in: Microbial cell factories (2021)
These data suggest that the molecular bases of protein aggregation are related to the net balance of protein aggregation potential and not only to the presence of APPs. This is then presented as a generic platform to generate hybrid protein aggregates in microbial cell factories for biopharmaceutical and biotechnological applications.