Cytomegalovirus viral load parameters associated with earlier initiation of pre-emptive therapy after solid organ transplantation.
Sheila LumleyCameron GreenHannah RaffertyColette SmithMark HarberJames O'BeirneGareth JonesDouglas ThorburnAileen MarshallTina ShahMohamed ZuhairEmily RothwellSowsan AtabaniTanzina HaquePaul D GriffithsPublished in: PloS one (2019)
Pre-emptive therapy initiated at the first sign of viraemia post-transplant significantly reduced the peak viral load but increased later episodes of viraemia, consistent with the hypothesis of reduced antigenic stimulation of the immune system.