Promising potential of [177Lu]Lu-DOTA-folate to enhance tumor response to immunotherapy-a preclinical study using a syngeneic breast cancer model.

Patrycja GuzikKlaudia SiwowskaHsin-Yu FangSusan CohrsPeter BernhardtRoger SchibliCristina Müller

Published in: European journal of nuclear medicine and molecular imaging (2020)

Application of [177Lu]Lu-DOTA-folate had a positive effect on the therapy outcome of anti-CTLA-4 immunotherapy. The results of this study may open new perspectives for future clinical translation of folate radioconjugates.

Keyphrases

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