Proteomic cardiovascular risk assessment in chronic kidney disease.
Rajat DeoRuth F DubinYue RenAshwin C MurthyJianqiao WangHaotian ZhengZihe ZhengHarold FeldmanHaochang ShouJosef CoreshMorgan GramsAditya L SurapaneniZeenat BhatJordana B CohenMahboob RahmanJiang HeSantosh L SarafAlan S GoPaul L KimmelRamachandran S VasanMark R SegalHongzhe LiPeter GanzPublished in: European heart journal (2023)
In two sizeable populations with CKD, a proteomic risk model for incident cardiovascular disease surpassed clinical risk models recommended in clinical practice, even after including estimated glomerular filtration rate. New biological insights may prioritize the development of therapeutic strategies for cardiovascular risk reduction in the CKD population.