In vitro antidiabetic, antioxidant, antimicrobial, and cytotoxic activity of Murraya koenigii leaf extract intercedes ZnO nanoparticles.
Avinash SharmaRupak NagraikBaskar VenkidasamyAzhar KhanKanika DultaPankaj Kumar ChauhanDeepak KumarDong-Soo ShinPublished in: Luminescence : the journal of biological and chemical luminescence (2022)
Nanotechnology is an emerging field with tremendous potential and usage of medicinal plants and green preparation of nanoparticles (NPs) is one of the widely explored areas. These have been shown to be effective against different biological activities such as diabetes mellitus, cancer, antioxidant, antimicrobial, etc. The current studies focus on the green synthesis of zinc NPs (ZnO NPs) from aqueous leaf extract of Murraya koenigii (MK). The synthesized Murraya koeingii zinc oxide NPs (MK ZnO NPs) were characterized using UV-visible spectroscopy, dynamic light scattering (DLS), Fourier transform infrared (FTIR) spectroscopy, field emission scanning electron microscopy (FESEM), energy-dispersive spectrum (EDS) and cyclic voltammetry (CV). The synthesized MK ZnO NPs were evaluated for their in vitro antidiabetic, antioxidant, antimicrobial, and cytotoxic activity. They demonstrated significant antidiabetic and cytotoxic activity, as well as moderate free-radical scavenging and antibacterial activity.
Keyphrases
- oxide nanoparticles
- electron microscopy
- room temperature
- quantum dots
- staphylococcus aureus
- oxidative stress
- high resolution
- reduced graphene oxide
- ionic liquid
- single molecule
- visible light
- papillary thyroid
- solid state
- squamous cell
- gold nanoparticles
- risk assessment
- adipose tissue
- childhood cancer
- glycemic control