Combining Wire Localization of Clipped Nodes with Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in Node-Positive Breast Cancer: Preliminary Results from a Prospective Study.
Alejandra García NovoaBenigno Acea-NebrilCarlota Díaz CarballadaAlberto Bouzón AlejandroCarmen CondeCarmen Cereijo GareaJosé Ramón VarelaPaz Santiago FreijanesSilvia Antolín NovoaLourdes Calvo MartínezInma DíazSofia Rodríguez MartínezJoaquin Mosquera OsesPublished in: Annals of surgical oncology (2020)
Several studies have evaluated the efficacy of various procedures for lymph node marking for women with prechemotherapy lymph node involvement. Most of the studies reported high identification rates (> 94.8%), with false negative rates of < 7%. Similarly, our study allows us to conclude that combined axillary marking (clip and SLNB) in patients with metastatic lymph node at diagnosis and NAC offers a high identification rate (100%) and a high correlation between the wire-marked lymph node and the SLN (80%). This procedure has enabled the suppression of ALND for a significant number of patients (73%).
Keyphrases
- lymph node
- sentinel lymph node
- neoadjuvant chemotherapy
- positive breast cancer
- end stage renal disease
- ejection fraction
- newly diagnosed
- prognostic factors
- early stage
- chronic kidney disease
- minimally invasive
- squamous cell carcinoma
- radiation therapy
- bioinformatics analysis
- case control
- ultrasound guided
- patient reported