Expression and Alteration Value of Long Noncoding RNA AB073614 and FER1L4 in Patients with Acute Myeloid Leukemia (AML).

Ali GanjiMahmood KhosraviGhasem MosayebiMilad GholamiAli GhazaviNafiseh KeshavarzianMohammad Sayyadi

Published in: Asian Pacific journal of cancer prevention : APJCP (2023)

The present study indicates that AB073614 and FER1L4 might serve as prognosis biomarkers in AML patients. However, further detailed examinations in this field are warranted. It is proposed that the likely mechanism of imbalanced PI3K and PTEN activity, triggered by the deregulation of AB073614 and FER1L4, may have a crucial role in AML pathogenesis. Any component of this pathway could potentially serve as a new target for more insightful treatment approaches.

Keyphrases

acute myeloid leukemia
long noncoding rna
allogeneic hematopoietic stem cell transplantation
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
combination therapy
smoking cessation