Prognostic value of tumor-associated N1/N2 neutrophil plasticity in patients following radical resection of pancreas ductal adenocarcinoma.
Qiangda ChenHanlin YinSiyao LiuSami ShoucairNi DingYuan JiJicheng ZhangDansong WangTiantao KuangXuefeng XuJun YuWenchuan WuNing PuWenhui LouPublished in: Journal for immunotherapy of cancer (2023)
The plasticity of tumor-associated N1/N2 neutrophils was identified as a crucial prognostic indicator that might reflect the TME and immune escape in patients with PDAC. On further investigation and validation, our findings may be used to further stratify patients with varying prognoses to optimize treatment.