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Frontal deficits and atrophy in a patient with familial encephalopathy with neuroserpin inclusion bodies detected by single-case voxel-based morphometry: a case report.

Hideo HandaAtsuhiko SugiyamaTadashi KanameYoko ShigemotoNoriko SatoShigeki HiranoYuki NakagawaAkiyuki UzawaAkiyo AotsukaSatoshi Kuwabara
Published in: BMC neurology (2024)
Frontal deficits including inattention and disinhibition can be the presenting symptoms of patients with FENIB. Single-case voxel-based morphometry may be useful for detecting regional atrophy of the frontal lobe in FENIB. Detecting these abnormalities in the early stage of disease may be key findings for differentiating FENIB from other causes of progressive myoclonic epilepsy.
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