Progressive Changes in Cerebral Apparent Diffusion Values in Fabry Disease: A 5-Year Follow-up MRI Study.
Koen P A BaasAlbert J EverardSimon KörverLaura van DussenBram F CoolenGustav J StrijkersCarla E M HollakAart J NederveenPublished in: AJNR. American journal of neuroradiology (2023)
Our results indicate that in Fabry disease, changes in diffusion precede the formation of white matter lesions and that microstructural changes progress faster in men compared with women. These findings suggest that DWI may be of predictive value for white matter lesion formation in Fabry disease.