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TEX15: A DNA repair gene associated with prostate cancer risk in Han Chinese.

Xiaoling LinZhongzhong ChenPeng GaoZhimei GaoHaitao ChenJun QiFang LiuDingwei YeHaowen JiangRong NaHongjie YuRong ShiDaru LuSiqun Lilly ZhengZengnan MoYinghao SunQiang DingJianfeng Xu
Published in: The Prostate (2017)
Our study provided preliminary evidence that the rare variant Q1631H in DNA repair gene TEX15 is associated with prostate cancer risk. This finding complements known common prostate cancer risk-associated variants and suggests the possible role of DNA repair genes in prostate cancer development.
Keyphrases
  • dna repair
  • prostate cancer
  • dna damage
  • copy number
  • genome wide
  • radical prostatectomy
  • genome wide identification
  • dna damage response
  • benign prostatic hyperplasia
  • dna methylation
  • gene expression