Relative contributions of mixed pathologies to cognitive and functional symptoms in brain donors exposed to repetitive head impacts.

Nicole SaltielYorghos TripodisTalia MenzinAliyah OlaniyanZach BaucomEukyung YhangJoseph N PalmisanoBrett MartinMadeline UretskyEvan NairBobak AbdolmohammadiArsal ShahRaymond NicksChristopher NowinskiRobert C CantuDaniel H DaneshvarBrigid DwyerDouglas I KatzRobert A SternVictor AlvarezBertrand HuberPatricia A BoyleJulie A SchneiderJesse MezAnn McKeeMichael L AloscoThor D Stein

Published in: Annals of neurology (2023)

In this sample of RHI-exposed brain donors with wide-ranging ages, multiple neuropathologies were common and correlated. Mixed neuropathologies, including CTE, underlie cognitive impairment in contact sport athletes. This article is protected by copyright. All rights reserved.

Keyphrases

cognitive impairment
resting state
white matter
functional connectivity
kidney transplantation
high frequency
cerebral ischemia
multiple sclerosis
physical activity