Novel curcumin nanoformulation induces apoptosis, and reduces migration and angiogenesis in liver cancer cells.

Steve M Harakeh Saber H Saber Rajaa Al-Raddadi Turki Al AmriSoad Al-JaouniMohammed QariYousef QariShafiul HaqueAyat ZawawiSoad S AliZakaria Y Abd Elmageed Shaker A Mousa

Published in: Artificial cells, nanomedicine, and biotechnology (2023)

Treatment of LC cells with Cur-NPs decreased cell proliferation, migration, and angiogenesis, and induced cell death by promoting the proapoptotic pathway.

Keyphrases

cell death
cell cycle arrest
endothelial cells
cell proliferation
high glucose
induced apoptosis
vascular endothelial growth factor
pi k akt
wound healing
mass spectrometry
simultaneous determination
oxidative stress
endoplasmic reticulum stress
signaling pathway
drug induced
high resolution mass spectrometry