(-)-Carvone Modulates Intracellular Calcium Signaling with Antiarrhythmic Action in Rat Hearts.

Gilmara Beatriz Andrade da Silva Diego Santos de SouzaJosé Evaldo Rodrigues Menezes-FilhoJúlio Alves da Silva-NetoJader Dos Santos CruzDanilo Roman CamposLucindo José Quintans-JúniorCarla Maria Lins de Vasconcelos

Published in: Arquivos brasileiros de cardiologia (2022)

(-)-Carvone decreases Ca2+ entry through L-type Ca2+ channels, reducing the cardiac contractility and intracellular Ca2+, and, therefore, presenting promising antiarrhythmic activity in the rat hearts.

Keyphrases

protein kinase
reactive oxygen species
left ventricular
catheter ablation
smooth muscle
atrial fibrillation