Genome-wide interaction study with smoking for colorectal cancer risk identifies novel genetic loci related to tumor suppression, inflammation and immune response.
Robert Carreras-TorresAndre E KimYi LinVirginia Díez-ObreroStephanie A BienConghui QuJun WangNiki L DimouElom Kouassivi AglagoDemetrios AlbanesVolker ArndtJames W BaurleySonja I BerndtStephane BezieauD Timothy Timothy BishopEmmanouil C BourasHermann BrennerArif BudiartoPeter T CampbellGraham CaseyAndrew T ChanJenny Chang-ClaudeXuechen ChenDavid V ContiChristopher H DampierMatthew A M DevallDavid A DrewJane C FigueiredoSteven J GallingerGraham G GilesStephen B GruberAndrea GsurMarc J GunterTabitha A HarrisonAkihisa HidakaMichael HoffmeisterJeroen R HuygheMark E JenkinsKristina M JordahlEric S KawaguchiTemitope O KekuAnshul KundajeLoic Le MarchandJuan Pablo LewingerLi LiBharuno MahesworoJohn L MorrisonNeil MurphyHongmei NanRami NassirPolly A NewcombMireia Obon-SantacanaShuji OginoJennifer OseRish K PaiJulie R PalmerNikos PapadimitriouBens PardameanAnita R PeoplesPaul David Peter PharoahElizabeth A PlatzGadi RennertEdward A Ruiz-NarvaezLori C SakodaPeter C ScacheriStephanie L SchmitRobert E SchoenAnna ShcherbinaMartha L SlatteryMariana C SternYu-Ru SuCatherine M TangenDuncan C ThomasYu TianKonstantinos K TsilidisCornelia M UlrichFranzel J B van DuijnhovenBethany Van GuelpenKala VisvanathanPavel VodickaTjeng Wawan CenggoroStephanie J WeinsteinEmily WhiteAlicja WolkMichael O WoodsLi HsuUlrike PetersVictor MorenoW James GaudermanPublished in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2022)
These findings can guide potential prevention treatments.