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Deep learning and manual assessment show that the absolute mitotic count does not contain prognostic information in triple negative breast cancer.

Maschenka C A BalkenholPeter BultDavid TellezWillem VreulsPieter C ClahsenFrancesco CiompiJeroen A W M van der Laak
Published in: Cellular oncology (Dordrecht) (2019)
Based on our results we conclude that the level of proliferation, as reflected by mitotic count, does not serve as a prognostic factor for TNBC. Therefore, TNBC patient management based on mitotic count should be discouraged.
Keyphrases
  • prognostic factors
  • cell cycle
  • deep learning
  • peripheral blood
  • signaling pathway
  • case report
  • cell proliferation
  • machine learning
  • healthcare
  • artificial intelligence