Genetic polymorphisms and their effects on the severity of silicosis in workers exposed to silica in Brazil.
Marcos César Santos de CastroAngela Santos Ferreira NaniKaio Cezar Rodrigues SalumJônatas de Mendonça RolandoJúlia Fernandes Barbosa Dos SantosHermano Albuquerque de CastroPatrícia Canto RibeiroWalter CostaCícero Brasileiro de MelloFabiana Barzotto KohlrauschPublished in: Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia (2022)
It appears that rs1800469 polymorphisms in the TGFB1 gene and rs763110 polymorphisms in the FASLG gene are involved in the severity of silicosis. Given the lack of studies relating genetic polymorphisms to the severity of silicosis, these results should be replicated in other populations.
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