Challenges and Discoveries in Polypharmacology of Neurodegenerative Diseases.
Teresa Carolliny Moreira Lustoza RodriguesNatália Ferreira de SousaAline Matilde Ferreira Dos SantosRenan Dantas Aires GuimarãesMarcus T ScottiLuciana Scotti
Published in: Current topics in medicinal chemistry (2023)
It was possible to identify several targets with pharmacological activities. Some of these targets had diseases in common such as carbonic anhydrase, acetylcholinesterase, NMDA, and MAO being relevant for possible multi-target approaches.