Aryl hydrocarbon receptor (AhR) activation contributes to high-fat diet-induced vascular dysfunction.
Josiane Fernandes SilvaJuliana A BolsoniRafael M da CostaJuliano V AlvesAlecsander F M BressanLuiz Eduardo V SilvaTiago Januario CostaAntonio E R OliveiraCarla P ManzatoCarlos A AguiarRubens FazanFernando de Queiroz CunhaHelder I NakayaFernando S CarneiroRita de Cássia TostesPublished in: British journal of pharmacology (2022)
AhR deletion attenuates HF diet-induced dyslipidaemia and vascular dysfunction by improving eNOS/NO signalling. Targeting AhRs may prevent obesity-associated vascular dysfunction.