Comorbidities, symptoms and end-of-life medication use in hospitalised decedents before and during the COVID-19 pandemic: a retrospective regional cohort study in Ottawa, Canada.

Peter G LawlorLeila CohenSamantha Rose AdeliElla BessererValérie GrattonRebekah MurphyGrace WarmelsAdrianna BruniMonisha KabirChelsea NoelBrandon HeidingerKoby AndersonKyle Arsenault-MehtaKrista WoollerJulie LapenskieColleen WebberDaniel BedardPaula EnrightIsabelle DesjardinsKhadija BhimjiClaire DyasonAkshai IyengarShirley H BushSarina IsenbergPeter TanuseputroBrandi Vanderspank-WrightJames DownarHenrique Parsons

Published in: BMJ open (2023)

COVID-19 decedents, particularly those in ICU, required higher EoL opioid and sedating medication doses than matched prepandemic or intrapandemic controls. These findings should inform and guide clinical practice.

Keyphrases

clinical practice
coronavirus disease
sars cov
chronic pain
intensive care unit
pain management
healthcare
mechanical ventilation
adverse drug
sleep quality
emergency department
community acquired pneumonia
depressive symptoms
physical activity