Identification of ER/SR resident proteins as biomarkers for ER/SR calcium depletion in skeletal muscle cells.

Lacey K GreerKatherine G MeilleurBrandon K HarveyEmily S Wires

Published in: Orphanet journal of rare diseases (2022)

Changes to the extracellular content caused by intracellular calcium dysregulation presents an opportunity for biomarker development and drug discovery.

Keyphrases

drug discovery
skeletal muscle
induced apoptosis
estrogen receptor
endoplasmic reticulum
cell cycle arrest
breast cancer cells
insulin resistance
patient safety
quality improvement
endoplasmic reticulum stress
signaling pathway
reactive oxygen species
oxidative stress
adipose tissue
cell proliferation
pi k akt