Dynamic Plasma Lipidomic Analysis Revealed Cholesterol Ester and Amides Associated with Sepsis Development in Critically Ill Patients after Cardiovascular Surgery with Cardiopulmonary Bypass.
Wenyan DingShaohang XuBao-Jin ZhouRuo ZhouPeng LiuXiangyi HuiYun LongLongxiang SuPublished in: Journal of personalized medicine (2022)
This study revealed characteristic lipidomic changes in the plasma of septic patients before and after cardiac surgery with CPB. We discovered two cholesterol esters and two amides from peripheral blood that could be promising signatures for sepsis within a dynamic detection between the preoperative and postoperative groups.
Keyphrases
- acute kidney injury
- peripheral blood
- end stage renal disease
- patients undergoing
- intensive care unit
- minimally invasive
- ejection fraction
- newly diagnosed
- septic shock
- single cell
- chronic kidney disease
- low density lipoprotein
- peritoneal dialysis
- gene expression
- coronary artery bypass
- genome wide
- patient reported outcomes
- patient reported