Anlotinib Suppresses Colorectal Cancer Proliferation and Angiogenesis via Inhibition of AKT/ERK Signaling Cascade.

Qian YangLaichao NiSaber ImaniZhangqiang XiangRui HaiRuilin DingShao Zhi FuJing Bo WuQinglian Wen

Published in: Cancer management and research (2020)

The findings of the present study suggested that anlotinib suppressed cell proliferation and angiogenesis via inhibition of AKT/ERK signaling pathway in colorectal cancer and could be a novel therapeutic strategy for treatment of CRC.

Keyphrases

signaling pathway
pi k akt
cell proliferation
endothelial cells
induced apoptosis
epithelial mesenchymal transition
vascular endothelial growth factor
cell cycle
wound healing
oxidative stress
smoking cessation