First-in-class positron emission tomography tracer for the glucagon receptor.

Irina VelikyanTorsten HaackMartin BossartAndreas EversIina LaitinenPhilip LarsenOliver PlettenburgLars JohanssonStefan PierrouMichael WagnerIrina Velikyan

Published in: EJNMMI research (2019)

[68Ga]Ga-DO3A-S01-GCG thus constitutes a first-in-class PET tracer targeting the GCG receptor, with suitable properties for clinical development. This tool has potential to provide direct quantitative evidence of GCG receptor occupancy in humans.

Keyphrases

positron emission tomography
pet ct
computed tomography
pet imaging
drug delivery
binding protein