Field evaluation of the novel One Step Malaria Pf and Pf/Pv rapid diagnostic tests and the proportion of HRP-2 gene deletion identified on samples collected in the Pwani region, Tanzania.

Zena E MwangonelaYoung YeQin RachelHajirani M MsuyaTunu G MwamlimaSarah S MswataProsper P ChakiEster G KimaroClement N MweyaMaxmillian G MpinaGrace W Mwangoka

Published in: Bulletin of the National Research Centre (2023)

One Step Malaria P.f/P.v Tri-line and One Step Malaria P.f rapid test kits have similar sensitivity and specificity as the standard mRDT that is currently in the market, demonstrating the potential to contribute in the fight against malaria in endemic settings. However, the identified malaria parasites population with HRP-2 gene deletion pose a threat to the current mRDT usability in the field and warrants further investigations.

Keyphrases

plasmodium falciparum
genome wide
copy number
healthcare
gene expression
risk assessment
genome wide identification
health information
human health
transcription factor
social media
structural basis