A greener approach towards the synthesis of N-heterocyclic thiones and selones using the mechanochemical technique.

This manuscript describes the synthesis of N-heterocyclic thiones and selones of a variety of imidazolium salts involving an eco-friendly and solventless ball-milling technique. The products have been isolated in almost quantitative yield, involving a minimum quantity of solvents only for the isolation of products by column chromatography, and in some cases for purification purposes. Both mono- and bisimidazolium salts afforded N-heterocyclic thiones and selones. The methodology is found to be superior in terms of reaction time, yield and energy efficiency as compared to conventional solution-state reactions.