Genetic analysis of impaired trimethylamine metabolism using whole exome sequencing.

Yiran GuoLiang-Dar HwangJiankang LiJason EadesChung Wen YuCorrine MansfieldAlexis Burdick-WillXiao ChangYulan ChenFujiko F DukeJianguo ZhangSteven FakharzadehPaul FennesseyBrendan J KeatingHui JiangHakon HakonarsonDanielle R ReedGeorge Preti

Published in: BMC medical genetics (2017)

Thus, variants in genes other than FMO3 may cause TMAU and the genetic variants identified here serve as a starting point for future studies of impaired TMA metabolism.

Keyphrases

copy number
genome wide
case control
transcription factor