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Antioxidant effect of Elamipretide on bull's sperm cells during freezing/thawing process.

Alicja MizeraEwa Czerniawska Piątkowska
Published in: Andrology (2021)
In conclusion, addition of the Elamipretide to the cryopreservation extender significantly improved frozen-thawed sperm cells quality and their function. The results of this study indicate that Elamipretide can be used as a cryoprotective agent to protect cells against the devastating effects of oxidative stress and increasing sperm survival after cryopreservation.
Keyphrases
  • induced apoptosis
  • oxidative stress
  • cell cycle arrest
  • endoplasmic reticulum stress
  • signaling pathway
  • quality improvement
  • anti inflammatory