The Impact of Gastroesophageal Reflux Disease and Proton Pump Inhibitor Use on the Risk of Repeat Catheter Ablation for Atrial Fibrillation.
Jennifer X CaiMiguel AlgaraWai-Kit LoSunil KapurWalter Wai-Yip ChanPublished in: Clinical and translational gastroenterology (2024)
GERD was an independent predictor for risk of repeat AF ablation within 1 year, even after controlling for major cardiovascular comorbidities and confounders. PPI therapy modulated this risk, as repeat ablation-free survival for PPI-treated GERD was noninferior to reflux-free patients.
Keyphrases
- catheter ablation
- atrial fibrillation
- gastroesophageal reflux disease
- left atrial
- free survival
- left atrial appendage
- newly diagnosed
- end stage renal disease
- oral anticoagulants
- direct oral anticoagulants
- percutaneous coronary intervention
- prognostic factors
- protein protein
- small molecule
- acute coronary syndrome
- venous thromboembolism
- mitral valve
- smoking cessation
- replacement therapy