Hypoxia-Directed Treatment of Human Papillomavirus-Related Oropharyngeal Carcinoma.
Nancy Y LeeEric J ShermanHeiko SchöderRick WrayJay O BoyleBhuvanesh SinghMilan GrkovskiRamesh PaudyalLouise CunninghamZhigang ZhangVaios HatzoglouNora KatabiBill H DiplasJames HanBrandon S ImberKhoi PhamYao YuKaveh ZakeriSean Matthew McBrideJung Julie KangChiaojung Jillian TsaiLinda C ChenDaphna Y GelblumJatin P ShahIan GanlyMarc A CohenJennifer R CracchioloLuc G T MorrisLara A DunnLoren S MichelJames V FettenAnuja KripaniDavid G PfisterAlan L HoAmita Shukla-DaveJohn L HummSimon N PowellBob T LiJorge S Reis-FilhoLuis A DiazRichard J WongNadeem RiazPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
Tumor hypoxia is a promising approach to direct dosing of curative-intent chemoradiotherapy for HPV-related carcinomas with preserved efficacy and substantially reduced toxicity that requires further investigation.