Idiosyncratic Drug-Induced Liver Injury in a Healthy Patient following PCSK9-Inhibitor Injection.

Bjoern-Ole StuebenD P HoyerS RadunzF SanerH SchmidtH A BabaJ W TreckmannL I Mazilescu

Published in: Case reports in hepatology (2024)

This is to our knowledge the first reported acute liver injury due to an inclisiran injection. Cortisol in combination with OPAL dialysis is an effective method for the treatment of acute liver injury caused by inclisiran injury, and in this case, it led to a near-complete reversal of the acute liver injury at the time of discharge.

Keyphrases

drug induced
liver injury
adverse drug
chronic kidney disease
case report
ultrasound guided
respiratory failure
end stage renal disease
hepatitis b virus
peritoneal dialysis
replacement therapy