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A Phase I/II Study of GSK525762 Combined With Fulvestrant in Patients With Hormone Receptor-Positive/HER2-Negative (HR+/HER2-) Advanced or Metastatic Breast Cancer.

David W CesconJohn HiltonSerafin Morales MurilloRachel M LaymanTimothy J PluardBelinda YeoIn Hae ParkLouise ProvencherSung-Bae KimYoung-Hyuck ImAnastasia WyceAnu Shilpa KrishnatryKirsty HicksQu ZhangOlena BarbashAhmed KhaledThierry HornerArindam DharMafalda OliveiraJoseph A Sparano
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Molibresib in combination with fulvestrant did not demonstrate clinically meaningful activity in this study.
Keyphrases
  • metastatic breast cancer
  • signaling pathway
  • cell proliferation