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Circulating 1,5-Anhydroglucitol as a Biomarker of ß-cell Mass Independent of a Diabetes Phenotype in Human Subjects.

Cecilia Jiménez-SánchezTeresa MezzaFlore SinturelLingzi LiGianfranco Di GiuseppeGiuseppe QueroFrançois R JornayvazIdris GuessousCharna DibnerPatrick SchrauwenSergio AlfieriAndrea GiaccariPierre Maechler
Published in: The Journal of clinical endocrinology and metabolism (2022)
In summary, plasma concentration of 1,5-anhydroglucitol follows the ß-cell mass and its noninvasive monitoring may alert about the loss of ß cells in subjects at risk for diabetes, an event that cannot be captured by other clinical parameters of glycemic control.
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