Host Mitochondrial Requirements of Cytomegalovirus Replication.
Chandler H MonkKevin J ZwezdarykPublished in: Current clinical microbiology reports (2020)
Emerging data suggests that cytomegalovirus relies on intact, functional host mitochondria for optimal replication. HCMV large size and slow replication kinetics create a dependency on mitochondria during replication. Targeting the host mitochondria is an attractive antiviral target.