Integrative genome analysis identified the KANNO blood group antigen as prion protein.

Yosuke OmaeShoichi ItoMayumi TakeuchiKazumi IsaKenichi OgasawaraKinuyo KawabataAkira OdaSayaka KaitoHatsue TsuneyamaMakoto UchikawaIkuo WadaHitoshi OhtoKatsushi Tokunaga

Published in: Transfusion (2019)

We first identified the coding gene of the high-frequency antigen KANNO located in PRNP and the missense variation (E219K) that affects the seropositivity of the KANNO antigen, which were confirmed by PRNP overexpressed cells.

Keyphrases

high frequency
transcranial magnetic stimulation
induced apoptosis
genome wide
cell cycle arrest
intellectual disability
copy number
autism spectrum disorder
dna methylation
protein protein
signaling pathway
endoplasmic reticulum stress
small molecule