The combination of tamoxifen with amphotericin B, but not with fluconazole, has synergistic activity against the majority of clinical isolates of Cryptococcus neoformans.
Trieu Phan HaiAnh Duong VanNguyen Thi Thuy NganLe Thanh Hoang NhatNguyen Phu Huong LanNguyen V Vinh ChauGuy E ThwaitesDamian KrysanJeremy N DayPublished in: Mycoses (2019)
Tamoxifen may be a useful addition to treatment with amphotericin and fluconazole for cryptococcal meningitis; a trial is justified.