Respiratory virus detection and sequencing from negative SARS-CoV-2 rapid antigen tests.

Emmanuela Jules Charlie Decker Brianna Jeanne Bixler Alaa AhmedZijing Carol ZhouItika Arora Henok TafesseHannah DakanayAndrei BombinEthan WangJessica IngersollKathy BifulcoJennifer K FredianiRichard ParsonsJulie Sullivan Morgan N Greenleaf Jesse J Waggoner Greg S Martin Wilbur A Lam Pardis Sabeti

Published in: medRxiv : the preprint server for health sciences (2024)

Genomic epidemiology offers important insight into the transmission and evolution of respiratory viruses. We used metagenomic sequencing from negative SARS-CoV-2 antigen tests to identify a wide range of respiratory viruses and generate full genome sequences, offering a streamlined mechanism for broad respiratory virus genomic surveillance.

Keyphrases

sars cov
respiratory tract
respiratory syndrome coronavirus
loop mediated isothermal amplification
copy number
genome wide
gene expression
dna methylation
label free
disease virus
anaerobic digestion