Bacterial Brain Abscesses Expand Despite Effective Antibiotic Treatment: A Process Powered by Osmosis Due to Neutrophil Cell Death.

Daniel DahlbergSverre HolmEllen Margaret Lund SagenAnnika Elisabet MichelsenMaria StenslandGustavo Antonio de SouzaEbba Gløersen MüllerJames Patrick ConnellyMona-Elisabeth RevheimBente HalvorsenBjørnar Hassel

Published in: Neurosurgery (2023)

Brain abscesses expand despite effective antibiotic treatment. Furthermore, brain abscesses cause lasting damage to surrounding brain tissue. These findings support drainage of brain abscesses within 24 hours of diagnosis.

Keyphrases

resting state
white matter
cell death
functional connectivity
cerebral ischemia
oxidative stress
multiple sclerosis
subarachnoid hemorrhage
brain injury
replacement therapy