Genetic characterisation of adult primary pleomorphic uterine rhabdomyosarcoma and comparison with uterine carcinosarcoma.
Charles W AshleyArnaud Da Cruz PaulaLorenzo FerrandoRodrigo Gularte-MéridaAna P M SebastiaoDavid N BrownAndrea M GazzoFresia ParejaAnthe StylianouNadeem R Abu-RustumJorge Sergio Reis-FilhoDarya BuehlerPaul WeismanSarah ChiangJorge S Reis-FilhoPublished in: Histopathology (2021)
Adult pleomorphic uRMSs harbour TP53 mutations and high levels of copy number alterations. Our findings underscore the challenge in discriminating between uRMS and UCS with rhabdomyosarcomatous differentiation.