Efficacy and safety of different fractions in stereotactic body radiotherapy for spinal metastases: A systematic review.

Yining GongLingyi XuHongqing ZhuangLiang JiangFeng WeiZhongjun LiuYan LiMiao YuKaiwen NiXiaoguang Liu

Published in: Cancer medicine (2019)

SBRT provided satisfactory efficacy and acceptable safety for spinal metastases. Single-fraction SBRT demonstrated a higher local control rate than those of the other factions, especially the 24 Gy dose. The risk of vertebral compression fracture (VCF) was slightly higher in single-fraction SBRT and more patients developed radiculopathy after multi-fraction SBRT.

Keyphrases

radiation therapy
end stage renal disease
spinal cord
ejection fraction
radiation induced
locally advanced
early stage
chronic kidney disease
prognostic factors
peritoneal dialysis
squamous cell carcinoma
bone mineral density
spinal cord injury
hip fracture