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An outbreak of relapsing fever unmasked by microbial paleoserology, 16th century, France.

Hamadou Oumarou HamaRémi BarbieriJacqueline GuirouThomas ChenalAurélie MayerYann ArdagnaMichel SignoliGérard AboudharamDidier RaoultMichel Drancourt
Published in: American journal of physical anthropology (2020)
Paleoserology unmasked an outbreak of relapsing B. recurrentis fever in one 16th - 17th century military garrison, missed by real-time PCR. Paleoserology offers a new tool for investigating past epidemics, in complement to DNA sequence-based approaches.
Keyphrases
  • real time pcr
  • multiple sclerosis
  • disease activity
  • microbial community
  • circulating tumor
  • cell free
  • single molecule
  • rheumatoid arthritis
  • posttraumatic stress disorder
  • amino acid