Response to SARS-CoV-2 vaccination in systemic autoimmune rheumatic disease depends on immunosuppressive regimen: a matched, prospective cohort study.
Peter MandlSelma TobudicHelmut HaslacherThomas KaronitschDaniel MrakThomas NothnaglThomas PerkmannHelga RadnerJudith SautnerElisabeth SimaderFlorian WinklerHeinz BurgmannDaniel AletahaStefan WinklerStephan BlümlPublished in: Annals of the rheumatic diseases (2022)
Patients with SARD showed a good response after the second vaccination with an mRNA vaccine. However, the choice of immunosuppressive medication has a marked effect on both SCR and overall antibody level, and the number of different immunomodulatory therapies determines vaccination response.